Notice
The primary rhythm figure is a fast 16th note figure which combines quick chordal accents with muted strings. Make sure your picking hand keeps a steady "down-up-down-up" stroke for each beat, sounding the chords on the appropriate accents. Keep this hand loose and set up a solid groove, giving the downbeats a little extra punch. Approach this part in a similar way to Stevie Ray Vaughan's intro on Couldn't Stand The Weather. In the fourth bar of the verse, the Bsus4 chord on the upbeat of two should be played by laying your pinky down momentarily.
One of the nicest things about the rhythm guitar part as a whole is the use of open strings in combination with fretted chords, such as the G(6) and B9/11 before the chorus and the Badd9 in the second bar of the chorus. The use of open strings in this way adds a full, ringing quality that is otherwise unattainable (the G(6) chord is reminiscent of the chords used by the Edge during the verse of Pride (in the Name of Love).
Overall, the rhythm guitar part should be played aggressively, with strong downbeat accents, and feel free to elaborate on the strumming patterns. Also, try substituting the little bass riff at the end of the verse (B,A,G,E) for the B9/11 chord.